DNA methylation is a biochemical process involving the addition of a methyl group to the cytosine. DNA methylation can alter gene expression and has become a promising area of research, since DNA methylation changes underlie many physiological conditions. We offer the Illumina Infinium MethylationEPIC beadchips V2 which include 935k methylation sites across the genome.
Alternatively, we offer the RRBS protocol. RRBS (Reduced Representation Bisulfite Sequencing) combines restriction enzyme digestion with bisulfite sequencing to enrich for a CpG-dense fraction of the genome and profile DNA methylation at single-nucleotide resolution.
We support each project from experimental design to advanced data analysis.
For Illumina Infinium Methylation please read the samples delivery instructions, fill and send us the electronic sample sheet.
For RRBS please read samples delivery instructions, fill and send us the electronic sample sheet.
For additional information, please contact:
Liat Linde, tel 073-3785452 or 073-3785168
Rappaport building 073-3785221
Emerson building 073-3781387